Accuracy

1. Optical Topographic Imaging for Spinal Intraoperative Three-Dimensional Navigation in Mini-Open Approaches: A Prospective Cohort Study of Initial Preclinical and Clinical Feasibility

Guha D, Jakubovic R, Alotaibi NM, et al. Optical topographic imaging for spinal intraoperative three-dimensional navigation in mini-open approaches: A prospective cohort study of initial preclinical and clinical feasibility. World Neurosurg. 2019;125:e863-e872. doi:10.1016/j.wneu.2019.01.201

  • Prospective clinical (n=8 patients, 55 screws) and cadaveric (n=4 cadavers, 37 screws) study investigating the accuracy of the 7D Surgical System with mini-open square exposures of 25-40 mm
  • Successful registration is dependent on number of surface points registered by the navigation system, not exposure size
  • 7D Surgical System showed comparable accuracy with mini-open exposures as with open exposures

2. Optical Topographic Imaging for Spinal Intraoperative 3-Dimensional Navigation in the Cervical Spine: Initial Preclinical and Clinical Feasibility 

Guha D, Jakubovic R, Alotaibi NM, et al. Optical Topographic Imaging for Spinal Intraoperative 3-Dimensional Navigation in the Cervical Spine: Initial Preclinical and Clinical Feasibility. Clin Spine Surg. 2019;32(7):303-308. doi:10.1097/BSD.0000000000000795

  • Prospective clinical (n=15 patients, 74 screws) and cadaveric (n=4 cadavers, 53 screws) study testing the accuracy of the 7D Surgical System in the cervical spine with an open posterior approach
  • 7D Surgical System showed comparable accuracy in the cervical spine as with open thoracolumbar procedures, and comparable accuracy to other spinal navigation systems

3. High Speed, High Density Intraoperative 3D Optical Surface Imaging with Efficient Registration to MRI and CT for Craniospinal Surgical Navigation 

Jakubovic R, Guha D, Gupta S, et al. High Speed, High Density Intraoperative 3D Optical Topographical Imaging with Efficient Registration to MRI and CT for Craniospinal Surgical Navigation. Sci Rep. 2018;8(1):1-12. doi:10.1038/s41598-018-32424-z

  • Prospective clinical study of 171 craniospinal surgical procedures comparing the 7D Surgical System to two legacy navigation systems indicates significant workflow improvement without compromising accuracy
  • Analysis of 162 pedicle screws found no significant differences between systems in breach rates and error between navigation systems
  • Decreased registration and setup time with the 7D Surgical System compared to other navigation systems (41s vs 258s and 794s), indicating increased workflow efficiency

4. Intraoperative Error Propagation in 3-Dimensional Spinal Navigation From Nonsegmental Registration: A Prospective Cadaveric and Clinical Study

Guha D, Jakubovic R, Gupta S, et al. Intraoperative Error Propagation in 3-Dimensional Spinal Navigation From Nonsegmental Registration: A Prospective Cadaveric and Clinical Study. Glob Spine J. 2018:219256821880455. doi:10.1177/2192568218804556

  • Prospective clinical (n=10 patients) and cadaveric (n=4 cadavers) study investigating accuracy of the 7D Surgical System when navigating distant to the spine reference frame and registered vertebral level
  • Average 3D navigation error is increased when navigating ≥ 2 levels from the reference frame because vertebral motion is unaccounted for
  • Navigating instruments within 2 levels of the reference frame minimizes the risk of navigation error

5. Novel Extended Vertebral Registration for Wrong-level spinal surgery – A Virtual Trial With Data Multiplexing Using Patient Specific Anatomy and Machine Vision Image Guidance (NEVER Wrong)

Zagzoog N, Guha D, Merali Z, Gupta S, Leung M, Yang VX. Novel Extended VErtebral Registration for Wrong-level spinal surgery – A Virtual Trial With Data Multiplexing Using Patient Specific Anatomy and Machine Vision Image Guidance (NEVER Wrong). In: Congress of Neurological Surgeons 2018 Annual Meeting. Houston, TX; 2018:813.

  • Identified a technique to use the 7D Surgical MvIGS system to reduce the incidence of wrong level spine surgery and improve patient care
  • Four detectors of wrong level spine surgery were tested with 310 measurements from 46 unique preclinical and clinical cases; each detector was able to determine if an indicated spine level was correct with 94% accuracy

6. Accuracy validation in the cervical spine of a Novel, Rapid, Optical Intraoperative Spinal Navigation System: Initial Clinical Feasibility

Guha D, Jakubovic R, Gupta S, Fehlings MG, Facs FC, Yee A. Accuracy Validation in the Cervical Spine of a Novel, Rapid, Optical Intraoperative Spinal Navigation System: Initial Clinical Feasibility. In: Congress of Neurological Surgeons 2016 Annual Meeting. San Diego, CA;2016:1321.

  • Retrospective review of 6 patients who underwent posterior cervical instrumentation, with a total of 22 screws navigated using the 7D Surgical System
  • Accuracy of the machine-vision system is comparable to other navigation systems but with a more efficient registration process that does not interrupt surgeon workflow

7. Quantification of computational geometric congruence in surface-based registration for spinal intra-operative three-dimensional navigation

Guha D, Jakubovic R, Leung MK, et al. Quantification of computational geometric congruence in surface-based registration for spinal intra-operative three-dimensional navigation. PLoS One. 2019;14(8):e0207137. doi:10.1371/journal.pone.0207137

  • Cadaveric (n=4) and clinical (n=11) study to quantify geometric symmetry in posterior spinal exposures and identify related potential predictors of navigation error
  • Geometric congruence is greatest at C1 and in the subaxial cervical spine, so navigation accuracy must be carefully verified at these levels following registration
  • Including the base of the spinous process in registrations improves accuracy due to decreased likelihood of geometric symmetry